Special regulatory T-cell review: T-cell dependent suppression revisited
نویسندگان
چکیده
منابع مشابه
Monoclonal regulatory T cells provide insights into T cell suppression
Regulatory T cells (Tregs) have a crucial role in maintaining lymphocyte homeostasis. However an understanding of how Tregs function at a cellular and molecular level has not yet been fully elucidated. Here, we make use of a T cell receptor (TCR) transgenic, Rag(-/-) mouse expressing a Forkhead-Box-Protein P3 (Foxp3) transgene. This mouse provides a source of monoclonal CD4(+) Foxp3(+) T cells ...
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ژورنال
عنوان ژورنال: Immunology
سال: 2008
ISSN: 0019-2805,1365-2567
DOI: 10.1111/j.1365-2567.2007.02772.x